Chris
Pirson
PhD FIBMS MISTR
Immune responses to the enduring hypoxic response antigen Rv0188 are preferentially detected in Mycobacterium bovis infected cattle with low pathology.
Jones GJ, Pirson C, Gideon HP, Wilkinson KA, Sherman DR, Wilkinson RJ, Hewinson RG, Vordermeier HM.
PLoS One. 2011 6(6):e21371. Epub 2011 Jun 21. PMID: 21712953
Vaccines designed to protect against Mycobacterium tuberculosis infection may aid the identification of novel vaccine constructs and diagnostic antigens for bovine tuberculosis.
Simultaneous measurement of antigen-stimulated interleukin-1 beta and gamma interferon production enhances test sensitivity for the detection of Mycobacterium bovis infection in cattle.
Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex.
Sidders B, Pirson C, Hogarth PJ, Hewinson RG, Stoker NG, Vordermeier HM, Ewer K.
Infect Immun. 2008 Sep;76(9):3932-9. Epub 2008 Jun 2. PMID: 18519559
publications
selected scientific
Differential effects of Mycobacterium bovis - derived polar and apolar lipid fractions on bovine innate immune cells.
Pirson C, Jones GJ, Steinbach S, Besra G, Vordermeier HM.
Vet Res. 2012 Jun 27;43(1):54. PMID: 22738036
Highly purified mycobacterial phosphatidylinositol mannosides drive cell mediated responses and activate NKT cells in cattle
Pirson C, Engel R, Jones GJ, Holder T, Holst O, Vordermeier HM.
Clin Vaccine Immunol. 2015 Feb;22(2):178-84. PMID: 25499010
A full list of Chris' publications is available on his ResearcherID and ResearchGate profiles